BioAdvanced Brush Killer Plus is a special penetrating formula that kills even the toughest brush and vine weeds, including kudzu, poison ivy, poison oak, blackberry and bramble. Plus, it kills more than 70 types of listed weeds systemically, to the root. It’s the easy, convenient way to eliminate unsightly brush, vines, brambles and listed weeds from your home’s landscape. Spray when brush is leafed out and actively growing. This selective systemic herbicide enters plants through their leaves, green or cut woody shoots, and roots then moves throughout the plant and interferes with processes found only in plants. Visual symptoms, such as wilting and yellowing, appear in 1 to 6 weeks. Controlling brush has never been easier. BioAdvanced. Get More From The Blue Bottle®.